I'd recommend the following upcoming webinar to prospective students interested in human neuroscience.
My laboratory studies the computational and neurophysiological basis of visual processing, using a wide range of computational and experimental techniques, including functional magnetic resonance imaging, patient studies, psychophysics and computational modeling.
Right now the lab has two main research directions. The first is plasticity in the visual system, including studies on perceptual learning in adulthood and the neural reorganization that occurs as a result of being blind or deaf.
The second is developing better stimulation protocols for retinal prostheses.
- June 16, 2022 Ione Fine was selected as the next Bloedel Scholar by UW's Virginia Merrill Bloedel Hearing Research Center
- April 27, 2021 Congratulations to Ione Fine and Geoffrey Boynton, who received a five-year, $1,880,561 award from the NIH National Eye Institute!
- June 27, 2020 Ione Fine, Alicia Izuierdo (UCLA) and Yael Niv (Princeton University) organized a virtual conference, which provides practical strategies for recognizing and overcoming implicit bias in labs and institutions
- May 8, 2019 Ione Fine and Kelly Chang are featured in this UW News story on how the brains of blind people adapt to increase hearing acuity.
- February 11, 2019 Ione Fine is featured in this Duke Research Blog article on overcoming judgement biases in STEM
- September 10, 2018 Congratulations to Michael Beyeler, a postdoc in Ione Fine's lab, who was recently awarded a K99 grant from National Eye Institute for research on virtual prototyping for retinal prosthesis patients.
- April 9, 2018 Vision Monday recently reported that Ione Fine will be the Keynote Speaker for the 13th annual Envision Conference
- March 8, 2018 A new study by Ione Fine and doctoral student Alicia Shen quantifies the glass ceiling for women in academic publishing.
- September 13, 2017 Ione Fine’s student, Ezgi Yucel, has just received a WRF Innovation Graduate Fellowship in Neuroengineering, co-funded with the eScience Institute, from the UW Institute of Neuroengineering. These fellowships are highly prestigious and selection is competitive. Congratulations, Ezgi!
- July 19, 2017 Congratulations to Ione Fine, who just received a 5 year award from the National Eye Institute for her research on the effects of blindness!
- January 4, 2017 Geoff Boynton and Ione Fine’s research on retinal implants cited in Mashable story about bionic eyes.
- August 5, 2015 Ione Fine and Geoff Boynton’s work on visual simulations using a bionic eye have been brought to light in an article by The Telegraph
- April 27, 2015 We aren’t the only ones who see the incredible work Ione Fine and Geoffrey Boynton are doing.
- October 10, 2011 Steve Buck, Ione Fine, and Geoff Boynton organized the Optical Society of America Vision Meeting, held on campus, September 15-18.
- January 31, 2011 Ione Fine received a Royalty Research Fund grant
- January 5, 2010 Ione Fine, Cheryl Kaiser, Scott Murray, and Joe Sisneros were approved by the College Council for promotion with tenure.
- November 3, 2009 Ione Fine was elected to be a Fellow of the Optical Society of America.
- Early Age-Related Hearing Loss Investigation (EARHLI): A Randomized Controlled Trial to Assess theMechanisms Linking Early Age-Related Hearing Loss and Alzheimer’s Disease and Related Dementias
- Learning to see again: biological constraints on cortical plasticity and the implications for sight restoration technologies
- Effects of Blindness on Human Early Visual Pathways
- The neural basis of individual differences in amblyopia: Neural assessment as a route to individualized treatment
- Go to http://www.ncbi.nlm.nih.gov/pubmed/?term=Fine%2C+Ione for up to date list of publications
- Blindness and Human Brain Plasticity.Fine I, Park JM.Early blindness causes fundamental alterations of neural function across more than 25% of cortex-changes that span the gamut from metabolism to behavior and collectively represent one of the most dramatic examples of plasticity in the human brain. The goal of this review is to describe how the remarkable behavioral and neuroanatomical compensations demonstrated by blind individuals provide insights into the extent, mechanisms, and limits of human brain Annu Rev Vis Sci. 2018
- Learning to see again: biological constraints on cortical plasticity and the implications for sight restoration technologies.Beyeler M, Rokem A, Boynton GM, Fine I.The 'bionic eye'-so long a dream of the future-is finally becoming a reality with retinal prostheses available to patients in both the US and Europe. However, clinical experience with these implants has made it apparent that the visual information provided by these devices differs substantially from normal sight. Consequently, the ability of patients to learn to make use of this abnormal retinal input plays a critical role in whether or not some functional vision is successfully regained. The goal of the present review is to summarize the vast basic science literature on developmental and adult cortical plasticity with an emphasis on how this literature might relate to the field of prosthetic vision. We begin with describing the distortion and information loss likely to be experienced by visual prosthesis users. We then define cortical plasticity and perceptual learning, and describe what is known, and what is unknown, about visual plasticity across the hierarchy of brain regions involved in visual processing, and across different stages of life. We close by discussing what is known about brain plasticity in sight restoration patients and discuss biological mechanisms that might eventually be harnessed to improve visual learning in these patients.Send toJ Neural Eng. 2017
- Pulse trains to percepts: the challenge of creating a perceptually intelligible world with sight recovery technologies.Fine I, Boynton GM.An extraordinary variety of sight recovery therapies are either about to begin clinical trials, have begun clinical trials, or are currently being implanted in patients. However, as yet we have little insight into the perceptual experience likely to be produced by these implants. This review focuses on methodologies, such as optogenetics, small molecule photoswitches and electrical prostheses, which use artificial stimulation of the retina to elicit percepts. For each of these technologies, the interplay between the stimulating technology and the underlying neurophysiology is likely to result in distortions of the perceptual experience. Here, we describe some of these potential distortions and discuss how they might be minimized either through changes in the encoding model or through cortical plasticity.